| Gene Symbol | Ppt1 |
|---|---|
| Entrez Gene | 29411 |
| Alt Symbol | Ppt |
| Species | Rat |
| Gene Type | protein-coding |
| Description | palmitoyl-protein thioesterase 1 |
| Other Description | PPT-1|palmitoyl-protein hydrolase 1 |
| Swissprots | P45479 A0JN20 |
| Accessions | EDL80359 EDL80360 P45479 BC126089 AAI26090 FQ213474 FQ213911 L34262 AAA59358 NM_022502 NP_071947 |
| Function | Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. |
| Subcellular Location | Lysosome. |
| Tissue Specificity | Highest amounts in brain, testis, lung, and spleen. Lowest amounts in liver and skeletal muscle. |
| Top Pathways | Lysosome, Fatty acid elongation, Fatty acid metabolism |