| Gene Symbol | ATP6V1B2 |
|---|---|
| Entrez Gene | 526 |
| Alt Symbol | ATP6B1B2, ATP6B2, HO57, VATB, VPP3, Vma2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 |
| Other Description | H+ transporting two-sector ATPase|V-ATPase B2 subunit|V-ATPase subunit B 2|V-type proton ATPase subunit B, brain isoform|endomembrane proton pump 58 kDa subunit|vacuolar H+-ATPase 56,000 subunit|vacuolar proton pump subunit B 2 |
| Swissprots | Q96IR0 Q15859 Q14544 P21281 D3DSQ5 B2R5Z3 |
| Accessions | CAA85522 CBX47579 EAW63758 EAW63759 P21281 AB208806 BAD92043 AK127443 AK294163 BAG57486 AK298819 BAG60951 AK312372 BAG35290 BC003100 AAH03100 BC007309 AAH07309 BC030640 AAH30640 DQ891837 ABM82763 DQ895023 ABM85949 L35249 AAA58661 M60346 AAA35610 X62949 CAA44721 NM_001693 NP_001684 |
| Function | Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. |
| Subcellular Location | Endomembrane system; Peripheral membrane protein. Melanosome. Note=Endomembrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Collecting duct acid secretion, Phagosome, Rheumatoid arthritis |