lias

Gene Symbol lias
Entrez Gene 443960
Alt Symbol LS, Lip-syn
Species Xenopus
Gene Type protein-coding
Description lipoic acid synthetase
Other Description LS|lip-syn|lipoate synthase|lipoic acid synthase|lipoyl synthase, mitochondrial
Swissprots Q6GQ48
Accessions CBN72481 Q6GQ48 BC072900 AAH72900 NM_001092065 NP_001085534
Function Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}.
Subcellular Location Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}.
Top Pathways Lipoic acid metabolism