ACSBG1

Gene Symbol ACSBG1
Entrez Gene 23205
Alt Symbol BG, BG1, BGM, GR-LACS, LPD
Species Human
Gene Type protein-coding
Description acyl-CoA synthetase bubblegum family member 1
Other Description bubblegum|lipidosin|long-chain-fatty-acid--CoA ligase ACSBG1|very long-chain acyl-CoA synthetase
Swissprots Q96GR2 Q9HC26 O75126 B2RB61 Q76N27
Accessions CBF65091 CBU89962 EAW99180 Q96GR2 AF070624 AF179481 AAG09404 AK054882 BAG51439 AK294202 BAH11696 AK295269 BAH12022 AK299597 BAH13077 AK314508 BAG37108 BC009289 AAH09289 BC040252 DC401742 DQ896428 ABM87427 EU176436 ABW03887 XM_011521389 XP_011519691 XM_011521390 XP_011519692 XM_011521391 XP_011519693 NM_001199377 NP_001186306 NM_015162 NP_055977
Function Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10954726}. Cytoplasmic vesicle {ECO:0000250}. Microsome {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}.
Tissue Specificity Expressed primarily in brain. Expressed at lower level in testis and adrenal gland. Present in all regions of brain except pituitary. {ECO:0000269|PubMed:10954726, ECO:0000269|PubMed:12975357}.
Top Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Fatty acid biosynthesis, Fatty acid degradation, Fatty acid metabolism