| Gene Symbol | ORC5 |
|---|---|
| Entrez Gene | 855460 |
| Alt Symbol | - |
| Species | Yeast |
| Gene Type | protein-coding |
| Description | origin recognition complex subunit 5 |
| Other Description | - |
| Swissprots | D6W0T2 P50874 |
| Accessions | DAA10298 P50874 NM_001183099 NP_014138 |
| Function | Component of the origin recognition complex (ORC) that binds origins of replication. It has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the ARS consensus sequence (ACS) of origins of replication. This subunit is a candidate for the mediation of ATP-dependent binding of ORC to origins. May also be a substrate targeting component of a cullin-RING-based E3 ubiquitin-protein ligase complex RTT101(MMS1-ORC5). {ECO:0000269|PubMed:18006685}. |
| Subcellular Location | Nucleus. |
| Top Pathways | Cell cycle - yeast, Meiosis - yeast |