ITPR3

Gene Symbol ITPR3
Entrez Gene 3710
Alt Symbol IP3R, IP3R3
Species Human
Gene Type protein-coding
Description inositol 1,4,5-trisphosphate receptor, type 3
Other Description IP3 receptor|inositol 1,4,5-triphosphate receptor, type 3|inositol 1,4,5-trisphosphate receptor type 3|insP3R3|type 3 InsP3 receptor
Swissprots Q5TAQ2 Q14649 Q14573
Accessions CBX47635 EAX03744 Q14573 AB209739 BAD92976 AK093524 AL832807 BC041398 BC146646 AAI46647 BC172406 AAI72406 CA430212 D26351 BAA05385 U01062 AAC50064 XM_011514576 XP_011512878 XM_011514577 XP_011512879 NM_002224 NP_002215
Function Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in intestinal crypt and villus epithelial cells.
Top Pathways cGMP-PKG signaling pathway, Circadian entrainment, Glucagon signaling pathway, Estrogen signaling pathway, Thyroid hormone synthesis