HAP4

Gene Symbol HAP4
Entrez Gene 853751
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description transcription factor HAP4
Other Description -
Swissprots D6VXH8 P14064
Accessions DAA09048 P14064 NM_001179675 NP_012813
Function Acts a component of the CCAT-binding factor, which is a transcriptional activator and binds to the upstream activation site (UAS2) of the CYC1 gene and other genes involved in mitochondrial electron transport and activates their expression. Recognizes the sequence 5'-CCAAT-3'. HAP4 encodes a regulatory subunit of the DNA-bound complex and seems to provide the principal transcriptional activation domains. Does not bind DNA directly, but augments the binding of HAP2 and HAP3. {ECO:0000269|PubMed:15075264, ECO:0000269|PubMed:2676721}.
Subcellular Location Nucleus.