| Gene Symbol | DRD2 |
|---|---|
| Entrez Gene | 1813 |
| Alt Symbol | D2DR, D2R |
| Species | Human |
| Gene Type | protein-coding |
| Description | dopamine receptor D2 |
| Other Description | D(2) dopamine receptor|dopamine D2 receptor|dopamine receptor D2 isoform|seven transmembrane helix receptor |
| Swissprots | P14416 Q9UPA9 Q9NZR3 |
| Accessions | AAA52328 AAB26274 AAC78779 BAC06078 CAB37869 CBJ06538 EAW67219 EAW67220 EAW67221 EAW67222 EAW67223 EAW67224 EAW67225 P14416 AB209832 BAD93069 AB451480 BAG70294 AF176812 AAF61479 AK308777 BC021195 AAH21195 BF437994 DA693976 DQ891920 ABM82846 DQ895104 ABM86030 M29066 AAA52761 M30625 AAA88023 S62137 AAB26819 S69899 AAB20571 X51362 CAA35746 X51645 CAB56463 NM_000795 NP_000786 NM_016574 NP_057658 |
| Function | Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. {ECO:0000269|PubMed:17264214, ECO:0000269|PubMed:21645528}. |
| Subcellular Location | Cell membrane {ECO:0000269|PubMed:21645528}; Multi-pass membrane protein {ECO:0000269|PubMed:21645528}. |
| Top Pathways | Gap junction, Dopaminergic synapse, Cocaine addiction, Alcoholism, cAMP signaling pathway |