| Gene Symbol | Lias |
|---|---|
| Entrez Gene | 305348 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | lipoic acid synthetase |
| Other Description | LS {ECO:0000255|HAMAP-Rule:MF_03123}|lip-syn {ECO:0000255|HAMAP-Rule:MF_03123}|lipoate synthase {ECO:0000255|HAMAP-Rule:MF_03123}|lipoic acid synthase {ECO:0000255|HAMAP-Rule:MF_03123}|lipoyl synthase, mitochondrial|lipoyl synthase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03123} |
| Swissprots | Q5XIH4 |
| Accessions | CBN72402 Q5XIH4 BC083708 AAH83708 XM_008770155 XP_008768377 XM_008770156 XP_008768378 NM_001012037 NP_001012037 |
| Function | Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. {ECO:0000255|HAMAP-Rule:MF_03123}. |
| Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03123}. |
| Top Pathways | Lipoic acid metabolism |