| Gene Symbol | CAMK2G |
|---|---|
| Entrez Gene | 818 |
| Alt Symbol | CAMK, CAMK-II, CAMKG |
| Species | Human |
| Gene Type | protein-coding |
| Description | calcium/calmodulin-dependent protein kinase II gamma |
| Other Description | caMK-II subunit gamma|calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma|calcium/calmodulin-dependent protein kinase type II subunit gamma |
| Swissprots | Q8N4I3 O15378 Q13282 Q13279 Q13555 Q5SQZ4 Q5SWX4 Q8NIA4 Q5SQZ3 Q7KYX5 O00561 Q13556 |
| Accessions | EAW54527 EAW54528 EAW54529 EAW54530 EAW54531 EAW54532 EAW54533 EAW54534 EAW54535 EAW54536 EAW54537 EAW54538 EAW54539 EAW54540 EAW54541 EAW54542 EAW54543 Q13555 AB209474 BAD92711 AK026309 AK094774 AK095576 BAG53089 AK131199 BAG54748 AK225771 AK291704 BAF84393 AK301180 BAG62765 BC012795 BC021269 AAH21269 BC034044 AAH34044 BC037928 BU165166 DQ892365 ABM83291 DQ895574 ABM86500 DQ896692 ABM87691 L07043 AAB61379 L07044 U32472 AAA75201 U32473 AAA75202 U32509 AAA75203 U50359 AAB16864 U50360 AAB16865 U66063 AAB80847 U66064 AAB80848 XM_005270195 XP_005270252 XM_005270197 XP_005270254 XM_005270198 XP_005270255 XM_005270199 XP_005270256 XM_005270200 XP_005270257 XM_005270201 XP_005270258 XM_005270202 XP_005270259 XM_005270203 XP_005270260 XM_005270205 XP_005270262 XM_006717993 XP_006718056 XM_006717995 XP_006718058 XM_006717996 XP_006718059 XM_006717997 XP_006718060 XM_006717998 XP_006718061 XM_006717999 XP_006718062 XM_006718000 XP_006718063 XM_011540224 XP_011538526 XM_011540225 XP_011538527 XM_011540226 XP_011538528 XM_011540227 XP_011538529 XM_011540228 XP_011538530 XM_011540229 XP_011538531 XM_011540230 XP_011538532 XM_011540231 XP_011538533 XR_945821 XR_945822 XR_945823 XR_945824 NM_001204492 NP_001191421 NM_001222 NP_001213 NM_172169 NP_751909 NM_172170 NP_751910 NM_172171 NP_751911 NM_172173 NP_751913 NM_172172 |
| Function | Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow- twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. {ECO:0000269|PubMed:16690701}. |
| Subcellular Location | Sarcoplasmic reticulum membrane {ECO:0000305}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Tissue Specificity | Expressed in skeletal muscle. {ECO:0000269|PubMed:16690701}. |
| Top Pathways | Wnt signaling pathway, Glucagon signaling pathway, Adrenergic signaling in cardiomyocytes, cAMP signaling pathway, Inflammatory mediator regulation of TRP channels |