GABRA2

Gene Symbol GABRA2
Entrez Gene 2555
Alt Symbol -
Species Human
Gene Type protein-coding
Description gamma-aminobutyric acid (GABA) A receptor, alpha 2
Other Description GABA(A) receptor subunit alpha-2|GABA(A) receptor, alpha 2|gamma-aminobutyric acid receptor subunit alpha-2
Swissprots Q59G14 B7Z1H8 A8K0U7 P47869
Accessions AAY40994 EAW93022 EAW93023 EAW93024 EAW93025 P47869 A28100 CAA01918 AB209295 BAD92532 AF086092 AK125179 BAG54159 AK289662 BAF82351 AK293466 BAH11514 AK307128 BC022488 AAH22488 BX108394 DB478542 DN991770 HG496881 JF432507 ADZ15724 S62907 AAB27278 XM_005248080 XP_005248137 XM_011513675 XP_011511977 XM_011513676 XP_011511978 NM_000807 NP_000798 NM_001114175 NP_001107647 NM_001286827 NP_001273756
Function GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Subcellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Top Pathways GABAergic synapse, Morphine addiction, Nicotine addiction, Retrograde endocannabinoid signaling, Neuroactive ligand-receptor interaction