PHO4

Gene Symbol PHO4
Entrez Gene 850594
Alt Symbol -
Species Yeast
Gene Type protein-coding
Description phosphate-sensing transcription factor PHO4
Other Description -
Swissprots D6VTR7 P07270
Accessions DAA12477 P07270 NM_001179999 NP_116692
Function Transcriptional activator that regulates the expression of repressible phosphatase under phosphate starvation conditions. Binds to the upstream activating sequence (UAS) of several phosphatase encoding PHO genes. Inhibited by the cyclin-CDK PHO80- PHO85 under high-phosphate conditions.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:8539622}. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981, ECO:0000269|PubMed:8539622}. Note=Predominantly cytoplasmic under high-phosphate conditions and localized to the nucleus upon phosphate starvation.
Top Pathways Cell cycle - yeast