| Gene Symbol | BT2 |
|---|---|
| Entrez Gene | 823994 |
| Alt Symbol | ATBT2, BTB and TAZ domain protein 2 |
| Species | Arabidopsis thaliana |
| Gene Type | protein-coding |
| Description | TAC1-mediated telomerase activation pathway protein BT2 |
| Other Description | - |
| Swissprots | Q9STL6 Q94BN0 |
| Accessions | AEE78407 CAW65690 CBC49883 CBD22520 Q94BN0 AK226596 BAE98711 AY040015 AAK64172 AY079408 AAL85139 AY316675 AAQ87005 BT000678 AAN31824 NM_114697 NP_566902 |
| Function | May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Plays a key role as a component of the TAC1- mediated telomerase activation pathway certainly by targeting a telomerase repressor to degradation. Seems to occupy an integral position in a complex signaling network that perceives, integrates, and responds to multiple, and sometimes competing, signals. Enhances responses to auxin in postgermination and vegetative development. Also negatively regulates ABA- and sugar- mediated inhibition of the germination. Essential for female and male gametophyte development. {ECO:0000269|PubMed:17220202, ECO:0000269|PubMed:19054356, ECO:0000269|PubMed:19525324}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:19054356}. Cytoplasm {ECO:0000269|PubMed:19054356}. |
| Tissue Specificity | Preferentially expressed in young leaves and roots. {ECO:0000269|PubMed:15316289, ECO:0000269|PubMed:19054356}. |
| Top Pathways | Stilbenoid, diarylheptanoid and gingerol biosynthesis, Limonene and pinene degradation |