| Gene Symbol | IL10 |
|---|---|
| Entrez Gene | 3586 |
| Alt Symbol | CSIF, GVHDS, IL-10, IL10A, TGIF |
| Species | Human |
| Gene Type | protein-coding |
| Description | interleukin 10 |
| Other Description | T-cell growth inhibitory factor|cytokine synthesis inhibitory factor|interleukin-10 |
| Swissprots | P22301 |
| Accessions | AAA80104 AAK19173 AAL06594 ABB01008 ACV30066 CAA51942 CAA55201 CAA82914 EAW93524 P22301 AF043333 AAC03534 AY029171 AAK38162 BC022315 BC104252 AAI04253 BC104253 AAI04254 CR541993 CAG46790 CR542028 CAG46825 EU751618 ACE95684 EU751619 ACE95685 M57627 AAA63207 XM_011509506 XP_011507808 NM_000572 NP_000563 |
| Function | Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. |
| Top Pathways | Inflammatory bowel disease (IBD), Tuberculosis, Pertussis, African trypanosomiasis, Epstein-Barr virus infection |