PSMC4

Gene Symbol PSMC4
Entrez Gene 5704
Alt Symbol MIP224, RPT3, S6, TBP-7, TBP7
Species Human
Gene Type protein-coding
Description proteasome (prosome, macropain) 26S subunit, ATPase, 4
Other Description 26S protease regulatory subunit 6B|26S proteasome AAA-ATPase subunit RPT3|MB67-interacting protein|Tat-binding protein 7|protease 26S subunit 6
Swissprots Q96FV5 Q9UEX3 Q9UBM3 P43686
Accessions AAD39267 EAW56928 EAW56929 P43686 AF020736 AAC32612 AF038965 AAC26843 AK290285 BAF82974 AK310135 AK313183 BAG36000 BC000343 AAH00343 BC010396 AAH10396 BC014488 AAH14488 BC018811 BI828251 BT007232 AAP35896 DQ891875 ABM82801 DQ894876 ABM85802 U27515 AAC99817 NM_006503 NP_006494 NM_153001 NP_694546
Function The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. {ECO:0000269|PubMed:8060531}.
Subcellular Location Cytoplasm. Nucleus.
Top Pathways Proteasome, Epstein-Barr virus infection