| Gene Symbol | GPX2 |
|---|---|
| Entrez Gene | 2877 |
| Alt Symbol | GI-GPx, GPRP, GPRP-2, GPx-2, GPx-GI, GSHPX-GI, GSHPx-2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | glutathione peroxidase 2 |
| Other Description | gastrointestinal glutathione peroxidase|glutathione peroxidase 2 (gastrointestinal)|glutathione peroxidase-related protein 2 |
| Swissprots | Q6PJ52 Q9NRP9 P18283 Q8WWI7 |
| Accessions | AAF74026 AAV31780 EAW80889 EAW80890 EAW80891 EAW80892 P18283 AK225871 BC005277 AAH05277 BC016756 AAH16756 BC022820 AAH22820 BC039850 BC046164 BC067221 AAH67221 BF207526 BG429974 X53463 CAB43534 X68314 CAA48394 NM_002083 NP_002074 NR_046320 NR_046321 |
| Function | Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors. |
| Subcellular Location | Cytoplasm. Note=Mainly cytoplasmic. |
| Tissue Specificity | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
| Top Pathways | Thyroid hormone synthesis, Glutathione metabolism, Arachidonic acid metabolism |