| Gene Symbol | ICAM2 |
|---|---|
| Entrez Gene | 3384 |
| Alt Symbol | CD102 |
| Species | Human |
| Gene Type | protein-coding |
| Description | intercellular adhesion molecule 2 |
| Other Description | ICAM-2 |
| Swissprots | Q14600 P13598 |
| Accessions | AAA36035 AAF34580 CAY39145 CDM22291 EAW94216 EAW94217 EAW94218 EAW94219 EAW94220 P13598 AB209878 BAD93115 AF340052 AAQ14909 AF340053 AAQ14910 AK223219 BAD96939 AK293110 BAF85799 AK295382 BAH12052 AK309953 BC003097 AAH03097 BM695682 BX363874 CA841927 CR541812 CAG46611 CR541834 CAG46633 DQ891843 ABM82769 DQ895031 ABM85957 X15606 CAA33630 NM_000873 NP_000864 NM_001099786 NP_001093256 NM_001099787 NP_001093257 NM_001099788 NP_001093258 NM_001099789 NP_001093259 |
| Function | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Natural killer cell mediated cytotoxicity, Cell adhesion molecules (CAMs) |