| Gene Symbol | MAN1A2 |
|---|---|
| Entrez Gene | 10905 |
| Alt Symbol | MAN1B |
| Species | Human |
| Gene Type | protein-coding |
| Description | mannosidase, alpha, class 1A, member 2 |
| Other Description | alpha-1,2-mannosidase IB|alpha1,2-mannosidase|mannosyl-oligosaccharide 1,2-alpha-mannosidase IB|processing alpha-1,2-mannosidase IB |
| Swissprots | Q9H510 O60476 |
| Accessions | AAC26200 AAC26201 EAW56675 EAW56676 O60476 AF027156 AAC26169 AK001970 BAG50997 AK090840 AK098129 AK307842 AU133800 BC015874 BC052954 BC063300 AAH63300 XM_006710302 XP_006710365 XM_011540536 XP_011538838 XR_946528 NM_006699 NP_006690 |
| Function | Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). |
| Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Highest levels of expression in placenta and testis. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum |