| Gene Symbol | IFNGR2 |
|---|---|
| Entrez Gene | 3460 |
| Alt Symbol | AF-1, IFGR2, IFNGT1, IMD28 |
| Species | Human |
| Gene Type | protein-coding |
| Description | interferon gamma receptor 2 (interferon gamma transducer 1) |
| Other Description | IFN-gamma receptor 2|IFN-gamma-R2|interferon gamma receptor 2|interferon gamma receptor accessory factor 1|interferon gamma receptor accessory factor-1|interferon gamma receptor beta chain|interferon gamma transducer 1 |
| Swissprots | Q9BTL5 P38484 |
| Accessions | AAC52066 AAT45458 CCF76939 EAX09834 EAX09835 P38484 AI824138 AK292246 BAF84935 AK314005 BAG36717 BC003624 AAH03624 BG391103 BQ008968 CB992729 DQ892320 ABM83246 DQ895522 ABM86448 EF173886 ABM53159 U05875 AAA16955 U05877 AAA16956 XM_005260969 XP_005261026 XM_011529553 XP_011527855 XM_011529554 XP_011527856 NM_005534 NP_005525 |
| Function | Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Salmonella infection, Inflammatory bowel disease (IBD), Tuberculosis, Herpes simplex infection, Cytokine-cytokine receptor interaction |