| Gene Symbol | Gad2 |
|---|---|
| Entrez Gene | 24380 |
| Alt Symbol | gad65 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | glutamate decarboxylase 2 |
| Other Description | 65 kDa glutamic acid decarboxylase|GAD-65|Glutamate decarboxylase 2 (islet)|glutamate decarboxylase 65 kDa isoform|glutamic acid decarboxylase 2|glutamic acid decarboxylase 65 |
| Swissprots | Q05683 |
| Accessions | AAC64947 EDL83940 EDL83941 Q05683 M72422 AAA63488 NM_012563 NP_036695 |
| Function | Catalyzes the production of GABA. |
| Subcellular Location | Cytoplasm, cytosol {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell junction, synapse, presynaptic cell membrane {ECO:0000250}; Lipid-anchor {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters (By similarity). {ECO:0000250}. |
| Top Pathways | Type I diabetes mellitus, GABAergic synapse, Taurine and hypotaurine metabolism, Alanine, aspartate and glutamate metabolism, beta-Alanine metabolism |