| Gene Symbol | CSH2 |
|---|---|
| Entrez Gene | 1443 |
| Alt Symbol | CS-2, CSB, PL, hCS-B |
| Species | Human |
| Gene Type | protein-coding |
| Description | chorionic somatomammotropin hormone 2 |
| Other Description | choriomammotropin|chorionic somatomammotropin B|lactogen|placental lactogen |
| Swissprots | P0DML3 |
| Accessions | AAA52116 AAA52553 AAA98747 ABZ88723 ABZ88724 ABZ88725 P0DML3 BC022044 AAH22044 BC035965 AAH35965 BC119748 AAI19749 CR615915 DQ892826 ABM83752 DQ896072 ABM87071 V00573 CAA23836 NM_020991 NP_066271 NM_022644 NP_072170 NM_022645 NP_072171 |
| Function | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. {ECO:0000269|PubMed:16546209}. |
| Subcellular Location | Secreted. |
| Top Pathways | Jak-STAT signaling pathway, PI3K-Akt signaling pathway, Neuroactive ligand-receptor interaction |