| Gene Symbol | ATP5G2 |
|---|---|
| Entrez Gene | 517 |
| Alt Symbol | ATP5A |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| Other Description | ATP synthase F(0) complex subunit C2, mitochondrial|ATP synthase c subunit|ATP synthase lipid-binding protein, mitochondrial|ATP synthase proteolipid P2|ATP synthase proton-transporting mitochondrial F(0) complex subunit C2|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9)|ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9)|ATPase protein 9|ATPase subunit C|mitochondrial ATP synthase, subunit C (subunit 9) |
| Swissprots | B3KQQ6 Q06055 |
| Accessions | CAA49533 EAW96725 EAW96726 Q06055 AK075351 BAG52118 AK130971 AK311357 AV737582 BC013839 BC020826 AAH20826 BF337574 BG217012 BQ682406 BX348847 D13119 BAA02421 D28402 BAA05768 DQ891367 ABM82293 DQ894547 ABM85473 H83751 M16439 AAA51804 XM_011538486 XP_011536788 NM_001002031 NP_001002031 NM_005176 NP_005167 |
| Function | Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. |
| Subcellular Location | Mitochondrion membrane; Multi-pass membrane protein. |
| Top Pathways | Alzheimer's disease, Huntington's disease, Oxidative phosphorylation |