| Gene Symbol | CSGALNACT2 |
|---|---|
| Entrez Gene | 55454 |
| Alt Symbol | CHGN2, GALNACT-2, GALNACT2, PRO0082 |
| Species | Human |
| Gene Type | protein-coding |
| Description | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| Other Description | beta 4 GalNAcT-2|chondroitin beta1,4 N-acetylgalactosaminyltransferase 2 |
| Swissprots | Q9P1I6 B3KWL7 Q6MZJ5 Q8N6G5 Q8TCH4 Q6MZP6 |
| Accessions | EAW86586 EAW86587 Q8N6G5 AA721408 AB079252 BAC55935 AB090811 BAC55936 AF086458 AF116646 AAF71068 AK074474 BAB85092 AK125300 BAG54179 BC030268 AAH30268 BX102005 BX640967 CAE45982 BX641073 CAE46036 BX647369 DA674683 DB291068 DQ891469 ABM82395 DQ894653 ABM85579 XM_011539938 XP_011538240 XM_011539939 XP_011538241 XR_945783 NM_018590 NP_061060 |
| Function | Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. {ECO:0000269|PubMed:12433924, ECO:0000269|PubMed:12446672}. |
| Subcellular Location | Golgi apparatus, Golgi stack membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:12433924, ECO:0000269|PubMed:12446672}. |
| Top Pathways | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate |