CTSS

Gene Symbol CTSS
Entrez Gene 1520
Alt Symbol -
Species Human
Gene Type protein-coding
Description cathepsin S
Other Description -
Swissprots Q6FHS5 D3DV05 P25774 B4DWC9 Q9BUG3 Q5T5I0
Accessions AAB60643 CCQ77674 EAW53517 EAW53518 EAW53519 P25774 AK024855 AK226095 AK301472 BAG62991 AK314482 BAG37086 BC002642 AAH02642 BQ006623 CR541676 CAG46477 M86553 AAA35655 M90696 AAC37592 S93414 AAB22005 NM_001199739 NP_001186668 NM_004079 NP_004070
Function Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
Subcellular Location Lysosome.
Top Pathways Lysosome, Phagosome, Tuberculosis, Antigen processing and presentation