CCBL1

Gene Symbol CCBL1
Entrez Gene 883
Alt Symbol GTK, KAT1, KATI
Species Human
Gene Type protein-coding
Description cysteine conjugate-beta lyase, cytoplasmic
Other Description beta-lysase, kidney|cysteine conjugate-beta lyase; cytoplasmic (glutamine transaminase K, kyneurenine aminotransferase)|cysteine-S-conjugate beta-lyase|glutamine transaminase K|glutamine--phenylpyruvate transaminase|glutamine-phenylpyruvate aminotransferase|kyneurenine aminotransferase|kynurenine aminotransferase I|kynurenine--oxoglutarate transaminase 1|kynurenine--oxoglutarate transaminase I
Swissprots Q16773 Q8N191 Q5T275
Accessions CAB44342 CAB44343 EAW87840 EAW87841 Q16773 AK094505 BAG52878 AK291178 BAF83867 AK297995 BAH12701 AK314427 BAG37043 AU123740 AW073815 BC013069 BC021262 AAH21262 BC022468 BC033685 AAH33685 BI755163 BM692880 BU622726 DA381449 DC413592 EL733697 X82224 CAA57702 XM_006717311 XP_006717374 XM_011519165 XP_011517467 XM_011519166 XP_011517468 XM_011519167 XP_011517469 XM_011519168 XP_011517470 XM_011519169 XP_011517471 XM_011519170 XP_011517472 XR_929870 NM_001122671 NP_001116143 NM_001122672 NP_001116144 NM_001287390 NP_001274319 NM_004059 NP_004050 NR_109829
Function Catalyzes the irreversible transamination of the L- tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Metabolizes the cysteine conjugates of certain halogenated alkenes and alkanes to form reactive metabolites. Catalyzes the beta- elimination of S-conjugates and Se-conjugates of L- (seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond. {ECO:0000269|PubMed:19338303}.
Subcellular Location Cytoplasm.
Top Pathways Chemical carcinogenesis, Selenocompound metabolism, Tryptophan metabolism