| Gene Symbol | BNIP1 |
|---|---|
| Entrez Gene | 662 |
| Alt Symbol | NIP1, SEC20, TRG-8 |
| Species | Human |
| Gene Type | protein-coding |
| Description | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| Other Description | BCL2/adenovirus E1B 19 kDa protein-interacting protein 1|transformation-related gene 8 protein|vesicle transport protein SEC20 |
| Swissprots | O75623 D3DQM3 D3DQM4 Q96FG4 O75622 D3DQM5 O75624 Q12981 Q6K044 D3DQM6 |
| Accessions | AAO61090 EAW61405 EAW61406 EAW61407 EAW61408 EAW61409 EAW61410 EAW61411 EAW61412 EAW61413 Q12981 AF083956 AAC33124 AF083957 AAC33125 AF083958 AAC33126 AU311051 AY216799 AAO91805 BC010959 AAH10959 BP384034 HQ448190 ADQ32671 U15172 AAC00020 XM_011534638 XP_011532940 XM_011534639 XP_011532941 NM_001205 NP_001196 NM_013978 NP_053581 NM_013979 NP_053582 NM_013980 NP_053583 |
| Function | SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Required for maintenance of ER network. Implicated in the suppression of cell death. May be involved in mitochondrial autophagy. {ECO:0000269|PubMed:15272311, ECO:0000269|PubMed:21931693}. |
| Subcellular Location | Mitochondrion. Endoplasmic reticulum membrane; Single-pass type IV membrane protein. |
| Tissue Specificity | Isoform 1 is highly expressed in heart, brain, liver skeletal muscle and pancreas. Isoform 3 is moderately expressed in placenta, lung and kidney. Isoform 4 is highly expressed in testis and small intestine. {ECO:0000269|PubMed:10217402}. |
| Top Pathways | SNARE interactions in vesicular transport |