MATALPHA2

Gene Symbol MATALPHA2
Entrez Gene 850406
Alt Symbol ALPHA2
Species Yeast
Gene Type protein-coding
Description Matalpha2p
Other Description -
Swissprots P0CY09 D6VQV2 Q6B2C0 P0CY08
Accessions NM_001178753 NP_009868
Function Mating type proteins are sequence specific DNA-binding proteins that act as master switches in yeast differentiation by controlling gene expression in a cell type-specific fashion. Transcriptional corepressor that binds cooperatively with MCM1 to a 31-basepair DNA sequence termed the a-specific gene (asg) operator, to repress the transcription of a-cell-specific genes. Additionally, in a/alpha diploid cells, binds cooperatively with the A1 protein to a 21-basepair DNA sequence termed the haploid- specific gene (hsg) operator, to repress transcription of haploid- specific genes and of MATALPHA1. {ECO:0000269|PubMed:8664541}.
Subcellular Location Nucleus.
Top Pathways Meiosis - yeast