| Gene Symbol | ATP6AP1 |
|---|---|
| Entrez Gene | 537 |
| Alt Symbol | 16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | ATPase, H+ transporting, lysosomal accessory protein 1 |
| Other Description | ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit 1|ATPase, H+ transporting, lysosomal interacting protein 1|H-ATPase subunit|V-ATPase Ac45 subunit|V-ATPase S1 accessory protein|V-ATPase subunit S1|V-type proton ATPase subunit S1|protein XAP-3|vacuolar proton pump subunit S1 |
| Swissprots | Q9H0C7 Q8NBT4 A6ZKI4 Q15904 |
| Accessions | EAW72712 EAW72713 EAW72714 EAW72715 Q15904 AK026519 AK075284 BAC11520 AK090462 BAC03443 AK091083 BAG52282 AK130616 AK289452 BAF82141 AK301603 BAG63090 AL136851 CAB66785 AM392567 CAL37445 AM393312 CAL38190 AM393872 CAL38747 BC000724 AAH00724 BC109247 BX461330 D16469 BAA03938 DA921677 DB569252 DQ892139 ABM83065 DQ895333 ABM86259 X87195 XM_011531179 XP_011529481 NM_001183 NP_001174 |
| Function | Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. {ECO:0000250}. |
| Subcellular Location | Vacuole membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. |
| Tissue Specificity | Ubiquitous. |
| Top Pathways | Epithelial cell signaling in Helicobacter pylori infection, Vibrio cholerae infection, Lysosome, Phagosome, Rheumatoid arthritis |