NT5E

Gene Symbol NT5E
Entrez Gene 4907
Alt Symbol CALJA, CD73, E5NT, NT, NT5, NTE, eN, eNT
Species Human
Gene Type protein-coding
Description 5'-nucleotidase, ecto (CD73)
Other Description 5'-NT|5'-nucleotidase|Purine 5-Prime-Nucleotidase|ecto-5'-nucleotidase
Swissprots P21589 Q5W116 B3KQI8 O75520
Accessions AAA96950 AAC98672 AAQ21035 CAF86213 CDM22274 EAW48634 EAW48635 EAW48636 P21589 AK075008 BAG52050 AK075083 BAG52063 AK314661 BAG37219 BC015940 AAH15940 BC065937 AAH65937 BQ019358 DA574510 DQ186653 ABA39834 X55740 CAA39271 NM_001204813 NP_001191742 NM_002526 NP_002517
Function Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities. {ECO:0000269|PubMed:21933152}.
Subcellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism