GTF2E2

Gene Symbol GTF2E2
Entrez Gene 2961
Alt Symbol FE, TF2E2, TFIIE-B
Species Human
Gene Type protein-coding
Description general transcription factor IIE, polypeptide 2, beta 34kDa
Other Description TFIIE-beta|general transcription factor IIE subunit 2|transcription initiation factor IIE subunit beta
Swissprots P29084 Q9H2B9 D3DSV2
Accessions AAG39077 EAW63446 EAW63447 EAW63448 EAW63449 P29084 BC001775 BC030572 AAH30572 S67861 AAB20414 X63469 CAA45069 XM_011544509 XP_011542811 XM_011544510 XP_011542812 NM_002095 NP_002086
Function Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
Subcellular Location Nucleus.
Top Pathways Viral carcinogenesis, Epstein-Barr virus infection, Basal transcription factors