ROT3

Gene Symbol ROT3
Entrez Gene 829790
Alt Symbol AP22.10, AP22_10, CYP90C1, ROTUNDIFOLIA 3
Species Arabidopsis thaliana
Gene Type protein-coding
Description 3-epi-6-deoxocathasterone 23-monooxygenase
Other Description -
Swissprots Q058J8 Q9M066 Q0WS16 O23242
Accessions AEE86649 CAW67788 CAW67806 CBC54106 CBC54144 CBD34584 Q9M066 BT029220 ABJ17155 NM_119801 NP_568002
Function C-23 hydroxylase involved in brassinosteroids biosynthesis. Converts directly (22S,24R)-22-hydroxy-5-alpha- ergostan-3-one and 3-epi-6-deoxocathasterone to 3-dehydro-6- deoxoteasterone and 6-deoxotyphasterol. These C-23 hydroxylation shortcuts bypass campestanol, 6-deoxocathasterone, and 6- deoxoteasterone. Functionally redundant with CYP90D1. {ECO:0000269|PubMed:15703058, ECO:0000269|PubMed:17138693}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15703058, ECO:0000269|PubMed:9694802}.
Top Pathways Brassinosteroid biosynthesis