| Gene Symbol | PSMC6 |
|---|---|
| Entrez Gene | 5706 |
| Alt Symbol | CADP44, HEL-S-73, P44, SUG2, p42 |
| Species | Human |
| Gene Type | protein-coding |
| Description | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| Other Description | 26S protease regulatory subunit 10B|26S protease regulatory subunit S10B|26S proteasome AAA-ATPase subunit RPT4|conserved ATPase domain protein 44|epididymis secretory protein Li 73|proteasome 26S subunit ATPase 6|proteasome subunit p42 |
| Swissprots | B2R975 Q92524 P62333 Q6IBU3 P49719 |
| Accessions | CAH05701 EAW65645 P62333 AA846884 AF006305 AAB61616 AK127456 AK299155 BAG61203 AK307087 AK313670 BAG36422 BC005390 AAH05390 BM788029 BP384173 BT006843 AAP35489 CR456709 CAG32990 D78275 BAA11338 DQ893704 ABM84630 FJ224299 ACI45991 XR_245706 XR_943495 NM_002806 NP_002797 |
| Function | The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. |
| Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Top Pathways | Proteasome, Epstein-Barr virus infection |