| Gene Symbol | Tat |
|---|---|
| Entrez Gene | 24813 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | tyrosine aminotransferase |
| Other Description | L-tyrosine:2-oxoglutarate aminotransferase |
| Swissprots | P04694 Q5EBB6 |
| Accessions | CAA09309 EDL92520 EDL92521 EDL92522 EDL92523 P04694 BC089813 AAH89813 M18340 AAA42203 X02741 CAA26519 NM_012668 NP_036800 |
| Function | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. {ECO:0000269|PubMed:1682164}. |
| Tissue Specificity | Liver. |
| Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis, Cysteine and methionine metabolism, Phenylalanine metabolism, Tyrosine metabolism, Biosynthesis of amino acids |