| Gene Symbol | SPCS2 |
|---|---|
| Entrez Gene | 9789 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | signal peptidase complex subunit 2 homolog (S. cerevisiae) |
| Other Description | SPase 25 kDa subunit|microsomal signal peptidase 25 kDa subunit|signal peptidase 25kDa subunit|signal peptidase complex subunit 2 |
| Swissprots | Q6IRX0 Q6FG65 Q6P1P4 Q96HU9 Q641R4 Q15507 Q15005 Q3KQT0 |
| Accessions | CAH05355 CAH05372 EAW74952 Q15005 AA921960 AK293128 BAG56680 BC008063 AAH08063 BC064957 AAH64957 BC067821 BC070276 AAH70276 BC082231 AAH82231 BC106066 AAI06067 BP338843 CR542233 CAG47029 CR542243 CAG47039 D14658 BAA03492 HQ448126 ADQ32607 NM_014752 NP_055567 |
| Function | Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}. |
| Subcellular Location | Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Protein export |