AQP9

Gene Symbol AQP9
Entrez Gene 366
Alt Symbol AQP-9, HsT17287, SSC1
Species Human
Gene Type protein-coding
Description aquaporin 9
Other Description aquaglyceroporin-9|aquaporin-9|small solute channel 1
Swissprots O43315 Q9NP32
Accessions AAF27983 CBJ05770 CBJ21222 EAW77532 EAW77533 EAW77534 O43315 AB008775 BAA24864 AF016495 AAF16677 AK300055 BAG61864 AK313214 BAG36029 BC026258 AAH26258 BE042553 CB528930 CR542027 CAG46824 DC410284 NM_020980 NP_066190
Function Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol. {ECO:0000269|PubMed:10564231}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in peripheral leukocytes. Also expressed in liver, lung, and spleen.
Top Pathways Bile secretion