| Gene Symbol | GATA3 |
|---|---|
| Entrez Gene | 2625 |
| Alt Symbol | HDR, HDRS |
| Species | Human |
| Gene Type | protein-coding |
| Description | GATA binding protein 3 |
| Other Description | GATA-binding factor 3|trans-acting T-cell-specific transcription factor GATA-3 |
| Swissprots | Q5VWG8 Q5VWG7 P23771 Q96J16 |
| Accessions | AAR32096 CAR95134 CAR95135 CBX53865 CBX53866 CDL93507 EAW86367 EAW86368 P23771 AI024501 AI686327 AK298213 BAG60483 AM392571 CAL37449 AM392688 CAL37566 BC003070 AAH03070 BC006793 AAH06793 BC006839 BG287052 BM152193 M69106 AAA35870 X55037 CAA38877 X55122 CAA38916 X58072 CAA41102 XM_005252442 XP_005252499 XM_005252443 XP_005252500 NM_001002295 NP_001002295 NM_002051 NP_002042 |
| Function | Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. {ECO:0000269|PubMed:23824597}. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | T-cells and endothelial cells. |
| Top Pathways | Inflammatory bowel disease (IBD) |