| Gene Symbol | CHAD |
|---|---|
| Entrez Gene | 1101 |
| Alt Symbol | SLRR4A |
| Species | Human |
| Gene Type | protein-coding |
| Description | chondroadherin |
| Other Description | cartilage leucine-rich protein|chondroadherin proteoglycan |
| Swissprots | O15335 A8K812 Q96RJ5 Q6GTU0 |
| Accessions | AAC13410 EAW94613 EAW94614 O15335 AF371328 AAK51556 AK292177 BAF84866 BC036360 AAH36360 BC073974 AAH73974 BQ181527 JF432155 ADZ15372 XM_011524214 XP_011522516 NM_001267 NP_001258 |
| Function | Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha(2)beta(1). May play an important role in the regulation of chondrocyte growth and proliferation (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250}. |
| Tissue Specificity | Present in chondrocytes at all ages. |
| Top Pathways | Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway |