GYPA

Gene Symbol GYPA
Entrez Gene 2993
Alt Symbol CD235a, GPA, GPErik, GPSAT, HGpMiV, HGpMiXI, HGpSta(C), MN, MNS, PAS-2
Species Human
Gene Type protein-coding
Description glycophorin A (MNS blood group)
Other Description MN sialoglycoprotein|Mi.V glycoprotein (24 AA)|erythroid-lineage-specific membrane sialoglycoprotein|glycophorin A (MN blood group)|glycophorin A, GPA|glycophorin Erik|glycophorin MiI|glycophorin MiV|glycophorin SAT|glycophorin Sta type C|glycophorin-A|recombinant glycophorin A-B Miltenberger-DR|sialoglycoprotein alpha
Swissprots A8K3E6 Q9BS51 B8Q185 P02724 B8Q182
Accessions AAA52623 AAA52768 AAA58616 AAA88045 AAC27543 AAC34718 AAC62525 AAC64483 AAG59990 AAR05989 AAR05990 AAR05991 AAR05992 AAR05993 AAR05994 AAR05995 AAR05996 AAR05997 AAR05998 AAX53134 AAX53136 AEP34039 AEP34040 AEP34041 AEP34042 AEP34043 AEP34044 AEP34045 AEP34046 AEP34047 AEP34048 AEP34049 AEP34050 AEP34051 AEP34052 AEP34053 AEP34054 AEP34055 AEP34056 AEP34057 AEP34058 AEP34059 AEP34060 AEP34061 AEP34062 AEP34063 AEP34064 AEP34065 AEP34066 AEP34067 AEP34068 AEP34069 AEP34070 AEP34071 AEP34072 AEP34073 AEP34074 AEP34075 AEP34076 AEP34077 AEP34078 AEP34079 AEP34080 AEP34081 AEP34082 AEP34083 AEP34084 AEP34085 AEP34086 AEP34087 AEP34088 AEP34089 AEP34090 AEP34091 AEP34092 AEP34093 AEP34094 AEP34095 AEP34096 AEP34097 AEP34098 AEP34099 AEP34100 AEP34101 AEP34102 AEP34103 AEP34104 AEP34105 AEP34106 AEP34107 AEP34108 AEP34109 AEP34110 AEP34111 AEP34112 AEP34113 AEP34114 AEP34115 AEP34116 AEP34117 AEP34118 AEP34119 AEP34120 AEP34121 AEP34122 AEP34123 AEP34124 AEP34125 AEP34126 AEP34127 AEP34128 AEP34129 AEP34130 AEP34131 AEP34132 AEP34133 AEP34134 AEP34135 AEP34136 AEP34137 AEP34138 AEP34139 AEP34140 AEP34141 AEP34142 AEP34143 AEP34144 AEP34145 AEP34146 AEP34147 AEP34148 AEP34149 AEP34150 AEP34151 AEP34152 AEP34153 AEP34154 AEP34155 AEP34156 AEP34157 AEP34158 AEP34159 AEP34160 AEP34161 AEP34162 AEP34163 AEP34164 AEP34165 AEP34166 AEP34167 AEP34168 AEP34169 AEP34170 AEP34171 AEP34172 AEP34173 AEP34174 AEP34175 AEP34176 AEP34177 AEP34178 AEP34179 AEP34180 AEP34181 AEP34182 AEP34183 AEP34184 AEP34185 AEP34186 AEP34187 AEP34188 AEP34189 AEP34190 AEP34191 AEP34192 AEP34193 AEP34194 AEP34195 AEP34196 AEP34197 AEP34198 AEP34199 AEP34200 AEP34201 AEP34202 AEP34203 AEP34204 AEP34205 AEP34206 AEP34207 AEP34208 AEP34209 AEP34210 AEP34211 AEP34212 AEP34213 AEP34214 AEP34215 AEP34216 AEP34217 AEP34218 AEP34219 AEP34220 AEP34221 AEP34222 AEP34223 AEP34224 AEP34225 AEP34226 AEP34227 AEP34228 AEP34229 AEP34230 AEP34231 AEP34232 AEP34233 AEP34234 AEP34235 AEP34236 AEP34237 AEP34238 AEP34239 AEP34240 AEP34241 AEP34242 AEP34243 AEP34244 AEP34245 AEP34246 AEP34247 AEP34248 AEP34249 AEP34250 AEP34251 AEP34252 AEP34253 AEP34254 AEP34255 AEP34256 AEP34257 AEP34258 AEP34259 AEP34260 AEP34261 AEP34262 AEP34263 AEP34264 AEP34265 AEP34266 AEP34267 AEP34268 AEP34269 AEP34270 AEP34271 AEP34272 AEP34273 AEP34274 AEP34275 AEP34276 AEP34277 AEP34278 AEP34279 AEP34280 AIY32612 CAA33821 CAC82326 CAC82327 CAC82328 CAC82329 CAC82330 CAC82331 CAC82332 CAC83868 CAC83869 CAC83870 CAC83871 CAC83934 CAC83935 CAC83936 CAC83937 CAC83938 CAC83939 CAC83940 CAC83941 CAC83942 CAC83943 CAC83944 CAC85268 CAC85269 CAC85270 CAC85271 CAC85272 CAC85273 CAC85274 CAC85275 CAC85276 CAC85277 CAC85278 CAC85279 CAC85280 CAC85281 CAC85282 CDO39028 EAX05061 EAX05062 P02724 AA334250 AI123404 AK290561 BAF83250 AY950614 AAX53135 BC005319 AAH05319 BC013328 AAH13328 BG497403 BX649043 DA537533 DA539682 DQ893046 ABM83972 EU338231 ACA96789 EU338232 ACA96790 EU338233 ACA96791 EU338234 ACA96792 GU347002 ADU25340 GU347003 ADU25341 GU347004 ADU25342 GU347005 ADU25343 GU347006 ADU25344 GU347007 ADU25345 GU347008 ADU25346 L07251 AAC46257 L07253 AAC46258 L31860 AAA88051 M12857 AAA88044 M36281 AAA52624 S77077 AAB34407 S77082 AAB34408 U00177 AAC50057 U00178 AAC50058 U00179 AAA18258 X08054 CAA30843 X51798 CAA36095 X57023 CAA40340 XM_011531902 XP_011530204 NM_001308187 NP_001295116 NM_001308190 NP_001295119 NM_002099 NP_002090
Function Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). {ECO:0000269|PubMed:10926825, ECO:0000269|PubMed:12813056, ECO:0000269|PubMed:14604989, ECO:0000269|PubMed:15331714, ECO:0000269|PubMed:19438409, ECO:0000269|PubMed:8009226}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:11402026}; Single-pass type I membrane protein {ECO:0000269|PubMed:11402026}. Note=Appears to be colocalized with SLC4A1.
Top Pathways Hematopoietic cell lineage, Malaria

Blood Group M antigen (1.B.710) - sc-70428 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Blood Group M antigen (GH-9) - sc-52373 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Blood Group M antigen (GH-9): sc-52373. Indirect FCM analysis of human erythrocytes stained with Blood Group M antigen (GH-9), followed by PE-conjugated goat anti-mouse IgM: sc-3768. Black line histogram represents the isotype control, normal mouse IgM: sc-3881.

Glycophorin A (H-12) - sc-166851 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (H-12): sc-166851. Western blot analysis of Glycophorin A expression in human PBL whole cell lysate (A) and human erythrocyte tissue extract (B).

Glycophorin A (E-18) - sc-19451 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Glycophorin A (H-60) - sc-20628 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Glycophorin A (H-60): sc-20628. Western blot analysis of human recombinant Glycophorin A fusion protein.

Glycophorin A (JC159) - sc-53295 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (JC159): sc-53295. Western blot analysis of Glycophorin A expression in K-562 whole cell lysate.

Glycophorin A (NaM10-6G4) - sc-51737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (NaM10-6G4): sc-51737. Western blot analysis of Glycophorin A expression in K-562 (A) and human PBL (B) whole cell lysates.

Glycophorin A (E4) - sc-59181 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (E4): sc-59181. Immunoperoxidase staining of formalin fixed, paraffin-embedded human blood vessel tissue showing membrane staining of erythrocytes.

Glycophorin A (R10) - sc-53905 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (R10): sc-53905. Western blot analysis of Glycophorin A expression in K-562 (A) and human PBL (B) whole cell lysates.

Glycophorin A (YTH89.1) - sc-59182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Glycophorin A (YTH89.1): sc-59182. Western blot analysis of Glycophorin A expression in human PBL (A) and K-562 (B) whole cell lysates.

Glycophorin A (C-20) - sc-19452 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Glycophorin A (C-20): sc-19452. Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing membrane localization.

Glycophorin A (5G119) - sc-71159 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (5G119): sc-71159. Western blot analysis of Glycophorin A expression in K-562 whole cell lysate.

Glycophorin A/B (HIR2) - sc-51603 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A (HIR2): sc-51603. Western blot analysis of Glycophorin A expression in K-562 whole cell lysate.

Glycophorin A/B (5F60) - sc-71158 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
Glycophorin A/B (5F60): sc-71158. Western blot analysis of Glycophorin A/B expression in K-562 whole cell lysate.

Anti-Glycophorin A + B antibody [HIR2] - ab15009 from Abcam

Prices $391.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HIR2
ab15009 staining Human normal lung tissue. Staining is localised to cellular membranes. Left panel: with primary antibody at 1 µg/ml. Right panel: isotype control. Sections were stained using an automated system DAKO Autostainer Plus, at RT. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 antigen retrieval buffer citrate pH 6.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins followed by blocking with Dako Protein block for 10 mins (containing casein 0.25% in PBS) then incubated with primary antibody for 20 mins and detected with Dako Envision Flex amplification kit for 30 mins. Colorimetric detection was completed with DAB for 5 mins. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-Glycophorin A + B antibody [HIR2] (Biotin) - ab93548 from Abcam

Prices $372.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone HIR2

Anti-Glycophorin A + B antibody [HIR2] (FITC) - ab52452 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HIR2

Anti-Glycophorin A + B antibody [HIR2] (Phycoerythrin) - ab26016 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HIR2

Anti-Glycophorin A antibody - ab40844 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-Glycophorin A antibody (ab40844) at 1 µg/ml + Human Liver lysate (35µg protein in RIPA buffer).

Anti-Glycophorin A antibody - ab128271 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Glycophorin A antibody (ab128271) at 1 µg/ml + Human fetal kidney lysate at 10 µg

Anti-Glycophorin A antibody [BRIC 256] - ab35760 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone BRIC 256

Anti-Glycophorin A antibody [EPR8199] - ab134111 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8199
Anti-Glycophorin A antibody [EPR8199] (ab134111) at 1/1000 dilution + Human fetal liver lysate at 10 µgSecondaryGoat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-Glycophorin A antibody [EPR8200] - ab129024 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8200
ab129024 staining Glycophorin A in Human placenta tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed and paraffin-embedded, antigen retrieval was by heat mediation in Tris/EDTA buffer pH9. Samples were incubated with primary antibody (1/2500). ab97051(1/500) HRP-conjugated goat anti-rabbit IgG(H&L) was used as the secondary antibody. Tissue counterstained with Hematoxylin. PBS was used in the negative control rather than the Primary antibody.

Anti-Glycophorin A antibody (FITC) - ab112201 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab112201, at 0.2 µg/106 cells, staining Glycophorin A in Human red blood cells by Flow Cytometry. Isotypic Control: FITC Rabbit IgG Percentage of cells stained above control: 99.2 %.

Anti-Glycophorin A antibody [HI264] (Allophycocyanin) - ab91163 from Abcam

Prices $189.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone HI264
ab91163, at 20 µl/106 cells, staining Glycophorin A in normal Human bone marrow by Flow cytometry.
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