| Gene Symbol | FH |
|---|---|
| Entrez Gene | 2271 |
| Alt Symbol | FMRD, HLRCC, LRCC, MCL, MCUL1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | fumarate hydratase |
| Other Description | fumarase|fumarate hydratase, mitochondrial |
| Swissprots | B1ANK7 P07954 |
| Accessions | AAP57532 EAW70090 EAW70091 EAW70092 EAW70093 P07954 AA669797 AK312415 BAG35325 AW611924 BC003108 AAH03108 BC017444 AAH17444 BT009839 AAP88841 DA129148 EU176358 ABW03809 M15502 AAA52483 U48857 AAD00071 U59309 AAB66354 XM_011544132 XP_011542434 NM_000143 NP_000134 |
| Function | Also acts as a tumor suppressor. |
| Subcellular Location | Isoform Mitochondrial: Mitochondrion. |
| Tissue Specificity | Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. {ECO:0000269|PubMed:22509282}. |
| Top Pathways | Citrate cycle (TCA cycle), Renal cell carcinoma, Pyruvate metabolism, Carbon metabolism |