CXCL8

Gene Symbol CXCL8
Entrez Gene 3576
Alt Symbol GCP-1, GCP1, IL8, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Species Human
Gene Type protein-coding
Description chemokine (C-X-C motif) ligand 8
Other Description T-cell chemotactic factor|alveolar macrophage chemotactic factor I|beta endothelial cell-derived neutrophil activating peptide|beta-thromboglobulin-like protein|emoctakin|granulocyte chemotactic protein 1|interleukin 8|interleukin-8|lung giant cell carcinoma-derived chemotactic protein|lymphocyte derived neutrophil activating peptide|monocyte-derived neutrophil chemotactic factor|monocyte-derived neutrophil-activating peptide|neutrophil-activating peptide 1|small inducible cytokine subfamily B, member 8|tumor necrosis factor-induced gene 1
Swissprots Q6LAE6 P10145 Q9C077 Q6FGF6 Q9UCR9 Q9UCR8 Q9UCE1 B2R4L8 Q96RG6 Q9UCS0
Accessions AAA59158 AAK60276 BAA03245 CBK51144 CBX54344 EAX05687 EAX05688 EAX05689 P10145 AJ227913 AK131067 AK311874 BAG34815 BC013615 AAH13615 BG497712 BT007067 AAP35730 CR542151 CAG46948 DQ890564 ABM92181 DQ893727 ABM84653 M17017 AAA35611 M23344 AAA74722 M26383 AAA36323 Y00787 CAA68742 Z11686 CAA77745 NM_000584 NP_000575
Function IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. {ECO:0000269|PubMed:11978786, ECO:0000269|PubMed:2145175, ECO:0000269|PubMed:2212672}.
Subcellular Location Secreted.
Top Pathways Malaria, Legionellosis, Salmonella infection, Influenza A, Non-alcoholic fatty liver disease (NAFLD)

IL-8 (C-11) - sc-376750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-8 (C-11): sc-376750. Western blot analysis of human recombinant IL-8.

IL-8 (5D8) - sc-101499 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal

IL-8 (3E4D8) - sc-32817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-8 (3E4D8): sc-32817. Western blot analysis of human recombinant IL-8.

IL-8 (C-19) - sc-1269 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
IL-8 (C-19): sc-1269. Western blot analysis of human recombinant human IL-8.

IL-8 (B-2) - sc-8427 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
IL-8 (B-2): sc-8427. Western blot analysis of human recombinant IL-8 fusion protein.

IL-8 (A-6) - sc-7302 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Western blot analysis of human recombinant IL-8 immunoprecipitated with IL-8 (A-6): sc-7302 and detected with IL-8 (C-19): sc-1269.

IL-8 (H-60) - sc-7922 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
IL-8 (H-60): sc-7922. Western blot analysis of human recombinant IL-8.

IL-8 (807) - sc-52870 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

IL-8 (NYR-HIL8) - sc-73321 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-IL8 antibody - ab7747 from Abcam

Prices $384.00
Sizes 500 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL8 antibody (ab7747) at 1 µg/mlLane 1 : Active human IL8 full length protein (ab73858) at 0.1 µgLane 2 : Active human IL8 full length protein (ab73858) at 0.01 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 5000 µg/mldeveloped using the ECL techniquePerformed under reducing conditions.Exposure time : 1 minute

Anti-IL8 antibody - ab10769 from Abcam

Prices $388.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab10769 staining IL8 in Human HUVEC cells by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with Triton X-100 0.1% in PBS and blocked with 10% serum for 30 minutes at 25°C. Samples were incubated with primary antibody (1/50 in culture medium) for 16 hours at 4°C. A Cy2®-conjugated Rabbit anti-goat polyclonal (1/500) was used as the secondary antibody.See Abreview

Anti-IL8 antibody - ab106350 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-IL8 antibody (ab106350) at 1 µg/mlLane 1 : Recombinant Human IL8 protein at 20ngLane 2 : Recombinant Human IL8 protein at 10ngLane 3 : Recombinant Human IL8 protein at 5ngLane 4 : Raji whole cell lysateLane 5 : MK (55kD)

Anti-IL8 antibody - ab84995 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL8 antibody (ab84995) at 1 µg/ml + Recombinant Protein:IL-8 at 0.1 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-IL8 antibody - ab118617 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-IL8 antibody (ab118617) at 1/500 dilution + Human fetal kidney lysate

Anti-IL8 antibody - ab154390 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-IL8 antibody (ab154390) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

Anti-IL8 antibody - ab117318 from Abcam

Prices $372.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-IL8 antibody - ab6684 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-IL8 antibody - ab9327 from Abcam

Prices $370.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-IL8 antibody - ab157749 from Abcam

Host Sheep
Clonality Polyclonal

Anti-IL8 antibody [6217] - ab10768 from Abcam

Prices $373.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6217

Anti-IL8 antibody [790A 28G2] (Biotin) - ab16224 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 790A 28G2

Anti-IL8 antibody [807] - ab18672 from Abcam

Prices $390.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 807
ab18672 staining IL8 in inflammed human temporal artery by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).Tissue was fixed in formaldehyde and an antigen retrieval step was performed using sodium citrate. Samples were then blocked with 5% serum for 1 hour at 25°C, then incubated with ab18672 at a 1/2000 dilution for 16 hours at 4°C. The secondary used was a rabbit anti-mouse polyclonal conjugated to biotin, 1/1000 dilution.See Abreview

Anti-IL8 antibody [AS14] - ab17268 from Abcam

Prices $372.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone AS14

Anti-IL8 antibody [AS15] (Biotin) - ab16165 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone AS15

Anti-IL8 antibody [B-K8] - ab11450 from Abcam

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-K8
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