NNMT

Gene Symbol NNMT
Entrez Gene 4837
Alt Symbol -
Species Human
Gene Type protein-coding
Description nicotinamide N-methyltransferase
Other Description -
Swissprots P40261
Accessions AAA93158 ACA06031 CAM12693 CDH92517 EAW67243 EAW67244 P40261 AA402535 AK026845 BC000234 AAH00234 BI255889 CR541907 CAG46705 DQ892841 ABM83767 DQ896088 ABM87087 U08021 AAA19904 NM_006169 NP_006160
Function Catalyzes the N-methylation of nicotinamide and other pyridines to form pyridinium ions. This activity is important for biotransformation of many drugs and xenobiotic compounds.
Subcellular Location Cytoplasm.
Tissue Specificity Predominantly expressed in the liver. A lower expression is seen in the kidney, lung, skeletal muscle, placenta and heart. Not detected in the brain or pancreas.
Top Pathways Nicotinate and nicotinamide metabolism