Pign

Gene Symbol Pign
Entrez Gene 27392
Alt Symbol Gm20308, PIG-N
Species Mouse
Gene Type protein-coding
Description phosphatidylinositol glycan anchor biosynthesis, class N
Other Description GPI ethanolamine phosphate transferase 1|phosphatidylinositol glycan, class N|phosphatidylinositol-glycan biosynthesis class N protein
Swissprots Q9R1S3 Q3V0S6 Q8VCC3 Q9R1S1 Q9R1S2
Accessions BAA82663 EDL39874 Q9R1S3 AB030279 BAA82619 AB030280 BAA82620 AK014165 AK082387 AK132928 BAE21427 AK165971 BC021148 AAH21148 XM_006529675 XP_006529738 XM_006529676 XP_006529739 XM_006529677 XP_006529740 XM_006529678 XP_006529741 XR_387174 XR_387175 NM_013784 NP_038812
Function Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. May act as suppressor of replication stress and chromosome missegregation. {ECO:0000269|PubMed:10574991}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:10574991}; Multi-pass membrane protein {ECO:0000269|PubMed:10574991}.
Top Pathways Glycosylphosphatidylinositol(GPI)-anchor biosynthesis