DAO

Gene Symbol DAO
Entrez Gene 102146162
Alt Symbol DAAO, DAMOX
Species Monkey
Gene Type protein-coding
Description D-amino-acid oxidase
Other Description hypothetical protein
Swissprots A2V9Y8
Accessions A2V9Y8 AK240621 BAF47375 NM_001283949 NP_001270878 XM_005572162 XP_005572219 XM_005572163 XP_005572220 XM_005572164 XP_005572221
Function Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (By similarity). {ECO:0000250}.
Subcellular Location Peroxisome {ECO:0000250}.
Top Pathways Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism