| Gene Symbol | CHKB |
|---|---|
| Entrez Gene | 1120 |
| Alt Symbol | CHETK, CHKL, CK, CKB, CKEKB, EK, EKB, MDCMC |
| Species | Human |
| Gene Type | protein-coding |
| Description | choline kinase beta |
| Other Description | choline kinase-like protein|choline/ethanolamine kinase|ethanolamine kinase beta |
| Swissprots | Q13388 Q9Y259 A0PJM6 |
| Accessions | AAB03342 BAA21491 BAA82511 EAW73573 EAW73574 EAW73575 Q9Y259 AB029886 BAA82512 AK097775 AK314324 BAG36972 AL096780 CAB46629 AL096781 CAB46630 BC024286 BC037162 BC050443 BC056404 BC082263 AAH82263 BC101488 AAI01489 BC113521 AAI13522 BE676287 CR456419 CAG30305 CU012980 CAK54411 CU013268 CAK54710 DB106393 HQ258226 ADR82980 NM_005198 NP_005189 NM_152253 |
| Function | Has a key role in phospholipid biosynthesis. Catalyzes the first step in phosphatidylethanolamine biosynthesis. Phosphorylates ethanolamine, and can also act on choline (in vitro). Has higher activity with ethanolamine. May not significantly contribute to in vivo phosphatidylcholine biosynthesis. {ECO:0000269|PubMed:19915674}. |
| Top Pathways | Choline metabolism in cancer, Glycerophospholipid metabolism |