| Gene Symbol | CYP11B2 |
|---|---|
| Entrez Gene | 1585 |
| Alt Symbol | ALDOS, CPN2, CYP11B, CYP11BL, CYPXIB2, P-450C18, P450C18, P450aldo |
| Species | Human |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 11, subfamily B, polypeptide 2 |
| Other Description | aldosterone synthase|aldosterone-synthesizing enzyme|cytochrome P-450Aldo|cytochrome P-450C18|cytochrome P450 11B2, mitochondrial|cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2|mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2|steroid 11-beta-monooxygenase|steroid 11-beta/18-hydroxylase|steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo |
| Swissprots | Q16726 P19099 B0ZBE4 |
| Accessions | AAA35741 AAB34642 AAB34643 ACA05912 BAA01040 BAA02899 EAW82292 P19099 BC111458 AAI11459 X54741 CAA38539 XM_011516877 XP_011515179 XM_011516878 XP_011515180 XM_011516879 XP_011515181 NM_000498 NP_000489 |
| Function | Preferentially catalyzes the conversion of 11- deoxycorticosterone to aldosterone via corticosterone and 18- hydroxycorticosterone. {ECO:0000269|PubMed:23322723}. |
| Subcellular Location | Mitochondrion membrane. |
| Top Pathways | Steroid hormone biosynthesis |