| Gene Symbol | GIF |
|---|---|
| Entrez Gene | 2694 |
| Alt Symbol | IF, IFMH, INF, TCN3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | gastric intrinsic factor (vitamin B synthesis) |
| Other Description | gastric intrinsic factor|intrinsic factor |
| Swissprots | B4DVZ1 P27352 B2RAN8 |
| Accessions | EAW73860 P27352 AK301290 BAG62848 AK301295 BAG62853 AK314275 BAG36935 BC037958 AAH37958 DQ892469 ABM83395 DQ895682 ABM86608 X76562 CAA54061 XM_011544939 XP_011543241 NM_005142 NP_005133 |
| Function | Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis. |
| Subcellular Location | Secreted. |
| Tissue Specificity | Gastric mucosa. |
| Top Pathways | Vitamin digestion and absorption |