Fut4

Gene Symbol Fut4
Entrez Gene 14345
Alt Symbol AI451562, CD15, FAL, FucT-IV, LeX, SSEA-1, Ssea1
Species Mouse
Gene Type protein-coding
Description fucosyltransferase 4
Other Description 3-fucosyl-N-acetyl-lactosamine epitope|Lewis x|alpha (1,3) fucosyltransferase, myeloid specific|alpha 1,3-fucosyltransferase|alpha-(1,3)-fucosyltransferase 4|fuc-TIV|fucosyltransferase IV|galactoside 3-L-fucosyltransferase|stage-specific embryonic antigen 1
Swissprots Q11127
Accessions AAC52269 BAA09697 BAB68648 BAB68650 BAB68651 BAB68652 BAB68653 BAB68654 BAB68655 BAB68656 EDL25001 Q11127 AK041752 BAC31054 BC137588 AAI37589 D63379 BAA09696 NM_010242 NP_034372
Function May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.
Subcellular Location Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Tissue Specificity Highest expression in stomach and colon. It is also expressed in the lung, testis, uterus, small intestine and to a lesser extent in spleen, and ovary. Present in trace amounts in brain, thymus, heart, smooth muscle, kidney and bone marrow. Not found in liver, salivary gland and pancreas.
Top Pathways Other types of O-glycan biosynthesis, Glycosphingolipid biosynthesis - lacto and neolacto series