| Gene Symbol | CYP3A7 |
|---|---|
| Entrez Gene | 1551 |
| Alt Symbol | CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA |
| Species | Human |
| Gene Type | protein-coding |
| Description | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| Other Description | aryl hydrocarbon hydroxylase|cytochrome P450 3A7|cytochrome P450, subfamily IIIA, polypeptide 7|cytochrome P450-HFLA|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase |
| Swissprots | P24462 Q9H241 A4D288 |
| Accessions | AAG32289 EAL23867 EAW76637 P24462 BC067436 AAH67436 BC069780 BX643367 BX647143 D00408 BAA00310 NM_000765 NP_000756 |
| Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
| Top Pathways | Steroid hormone biosynthesis, Chemical carcinogenesis, Retinol metabolism |