ATP4A

Gene Symbol ATP4A
Entrez Gene 495
Alt Symbol ATP6A
Species Human
Gene Type protein-coding
Description ATPase, H+/K+ exchanging, alpha polypeptide
Other Description ATPase, H+/K+ transporting, alpha polypeptide|H(+)-K(+)-ATPase alpha subunit|gastric H(+)/K(+) ATPase subunit alpha|gastric H+/K+ ATPase alpha subunit|gastric H,K-ATPase alpha subunit|gastric H,K-ATPase catalytic subunit|gastric hydrogen-potassium ATPase|potassium-transporting ATPase alpha chain 1|proton pump
Swissprots P20648 O00738
Accessions AAA35577 AAA35988 AAA51010 AAB50172 AAB64182 P20648 AK058032 AK223259 BAD96979 AK308474 AL832971 CAH56338 BC167780 AAI67780 NM_000704 NP_000695
Function Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Found in gastric mucosa.
Top Pathways Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation