ENTPD3

Gene Symbol ENTPD3
Entrez Gene 956
Alt Symbol CD39L3, HB6, NTPDase-3
Species Human
Gene Type protein-coding
Description ectonucleoside triphosphate diphosphohydrolase 3
Other Description CD39 antigen-like 3|NTPDase 3|ecto-ATP diphosphohydrolase 3|ecto-ATPDase 3|ecto-ATPase 3|ecto-apyrase 3
Swissprots O75355 Q8N6K2 G5E9N0 B2R8D0 O60495
Accessions EAW64600 EAW64601 O75355 AF034840 AAC09236 AF039917 AAC39884 AK313322 BAG36127 BC029869 AAH29869 BX952692 DA209533 XM_005265607 XP_005265664 XM_011534266 XP_011532568 XR_245167 XR_427297 XR_940520 NM_001248 NP_001239 NM_001291960 NP_001278889 NM_001291961 NP_001278890
Function Has a threefold preference for the hydrolysis of ATP over ADP.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes.
Top Pathways Epstein-Barr virus infection, Purine metabolism, Pyrimidine metabolism